Antimicrobials for treating symptomatic non-typhoidal Salmonella infection

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There appears to be no evidence of a clinical benefit of antibiotic therapy in otherwise healthy children and adults with non-severe salmonella diarrhoea. Antibiotics appear to increase adverse effects and they also tend to prolong salmonella detection in stools.

Non-typhoidal salmonellosis appears to be an important cause of acute diarrhoea in some developing countries. Antibiotic treatment of salmonellosis aims to shorten illness and prevent serious complications. There are also concerns about increasing antibiotic drug resistance. This review assesses the effects of antibiotics in adults and children with diarrhoea who have salmonellosis.

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