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Interventions for promoting smoke alarm ownership and function

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This review found that programmes to promote smoke alarms have at most modest beneficial effects on smoke alarm ownership and function, and no demonstrated beneficial effect on fires or fire-related injuries.
Globally, fire-related burns and smoke inhalation accounted for 238,000 deaths in 2000, …

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Topical negative pressure (TNP) for partial thickness burns

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There is no evidence regarding the use of topical negative pressure (TNP) for treating partial thickness burn wounds.
Treatments for burns include a variety of dressings, but newer strategies such as TNP therapy have been developed to try to promote the wound …

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Probiotics for treating persistent diarrhoea in children

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There is limited evidence suggesting probiotics may be effective in treating persistent diarrhoea in children.
Persistent diarrhoea (diarrhoea lasting more than 14 days) accounts for one third of all diarrhoea-related deaths in developing countries in some studies, and probiotics may help treatment. This …

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Probiotics for treating acute infectious diarrhoea

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Used alongside rehydration therapy, probiotics appear to be safe and have clear beneficial effects in shortening the duration and reducing stool frequency in acute infectious diarrhoea. However, more research is needed to guide the use of particular probiotic regimens in specific patient …

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Oral zinc for treating diarrhoea in children

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In areas where the prevalence of zinc deficiency or the prevalence of moderate malnutrition is high, zinc may be of benefit in children aged six months or more.The current evidence does not support the use of zinc supplementation in children below six …

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Oral versus intravenous rehydration for treating dehydration due to gastroenteritis in children

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There were no important clinical differences between oral rehydration therapy and intravenous rehydration therapy for rehydration secondary to acute gastroenteritis in children.
Dehydration associated with gastroenteritis is a serious complication. Dehydration occurs when body water content is reduced causing dry skin, headaches, sunken …

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Reduced osmolarity oral rehydration solution for treating dehydration caused by acute diarrhoea in children

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In children admitted to hospital with diarrhoea, reduced osmolarity ORS [total osmolarity ≤ 250 mmol/L with reduced sodium] when compared to WHO standard ORS [90 mmol/L sodium, 111 mmol/L glucose, total osmolarity 311 mmol/L] is associated with fewer unscheduled intravenous fluid infusions, …

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Antibiotic prophylaxis for leptospirosis

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Regular use of weekly doxycycline 200 mg oral therapy has increased odds for nausea and vomiting with unclear benefit in reducing Leptospira seroconversion or clinical consequences of infection. If it is efficacious in reducing disease, it may be more so in …

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Oral treatments for fungal infections of the skin of the foot

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The evidence suggests that terbinafine is more effective than griseofulvin and that terbinafine and itraconazole are more effective than no treatment.
About 15% of the population have fungal infections of the feet (tinea pedis or athlete’s foot). While there are many clinical …

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Topical treatments for fungal infections of the skin and nails of the foot

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Placebo-controlled trials of allylamines and azoles for athlete’s foot consistently produce much higher percentages of cure than placebo. Allylamines cure slightly more infections than azoles and are now available OTC [over the counter]. Further research into the effectiveness of antifungal agents …

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