» Person groups

Oral treatments for fungal infections of the skin of the foot

Read the full article
The evidence suggests that terbinafine is more effective than griseofulvin and that terbinafine and itraconazole are more effective than no treatment.
About 15% of the population have fungal infections of the feet (tinea pedis or athlete’s foot). While there are many clinical presentations …

Full Story »

Topical treatments for fungal infections of the skin and nails of the foot

Read the full article
Placebo-controlled trials of allylamines and azoles for athlete’s foot consistently produce much higher percentages of cure than placebo. Allylamines cure slightly more infections than azoles and are now available OTC [over the counter]. Further research into the effectiveness of antifungal agents for …

Full Story »

Antibiotics for treating scrub typhus

Read the full article
There are no obvious differences between tetracycline, doxycycline, telithromycin, or azithromycin; rifampicin may be better than tetracycline in areas where scrub typhus appears to respond poorly to standard anti-rickettsial drugs.
Scrub typhus is a bacterial infection transmitted by chiggers (mites). The infection causes …

Full Story »

Interventions for trachoma trichiasis

Read the full article
No trials show interventions for trichiasis prevent blindness. Certain interventions have been shown to be more effective at eliminating trichiasis.
Repeated infections cause scarring of the conjunctiva of the upper eyelid, which causes the eyelid to turn in (entropion) so that the eyelashes …

Full Story »

Face washing promotion for preventing active trachoma

Read the full article
Evidence from one trial suggests that face washing can be effective in increasing facial cleanliness and in reducing severe trachoma, but its effect in reducing active trachoma is inconclusive. In another trial, there was no evidence of effect of face washing alone …

Full Story »

Environmental sanitary interventions for preventing active trachoma

Read the full article
The role of insecticide spray as a fly control measure in reducing trachoma remains unclear. There is some evidence from two trials that insecticides are effective in reducing transmission of trachoma, but not demonstrated in another trial that also used insecticides. Health …

Full Story »

Antibiotics for trachoma

Read the full article
The review found some evidence that antibiotics reduce trachoma. Ointment is neither better nor worse than tablets.
In 1997, WHO launched an initiative on trachoma control based on the SAFE strategy (surgery, antibiotics, facial cleanliness, and environmental improvement). This review aims to assess …

Full Story »

Antibiotics versus placebo for acute bacterial conjunctivitis

Read the full article
Acute bacterial conjunctivitis is frequently a self-limiting condition, but the use of antibiotics is associated with modestly improved rates of clinical and microbiological remission compared to placebo.
Acute bacterial conjunctivitis is an infective condition in which the eyes become red and inflamed. The …

Full Story »

Interventions for impetigo

Read the full article
There is good evidence that topical mupirocin and topical fusidic acid are equally, or more, effective than oral treatment. Due to the lack of studies in people with extensive impetigo, it is unclear if oral antibiotics are superior to topical antibiotics in …

Full Story »

Interventions for treating scabies

Read the full article
On the basis of the available evidence from randomized controlled trials, topical permethrin appears to be the most effective treatment for scabies. Ivermectin appears to be an effective oral treatment, but in many countries it is not licensed for this indication.
Scabies is …

Full Story »