Dilute versus full strength formula in exclusively formula-fed preterm or low birth weight infants

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The available evidence on the reduction in time taken for infants to attain an adequate energy intake as a result of use of dilute formula is based on three small low quality studies. No evidence was reported on outcomes such as gastrointestinal problems. Also, on the outcome of feeding intolerance, no evidence of important differences between the dilute and full strength formulae was found.

The aim of the review was to assess the effects of dilute versus full strength formulae on the incidence of necrotising enterocolitis, feeding intolerance, weight gain, length of stay and time to achieve full calorie intake in exclusively formula-fed preterm or low birth weight infants. Additionally, it aimed to assess the effects of different dilution strategies.

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