Selenium supplementation for critically ill adults

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There is limited evidence to recommend supplementation of critically ill patients with selenium or ebselen.

Selenium is a trace mineral essential to health and has an important role in immunity, defence against tissue damage and thyroid function. Improving selenium status could help protect against overwhelming tissue damage and infection in critically ill adults. This review assesses the effects of selenium supplementation, including the selenium-containing compound ebselen, on adults recovering from critical illness.

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