Zika Virus Disease Epidemics

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Zika virus infection has probably been underdiagnosed and underreported in disease-endemic settings.

Zika is a mosquito-borne viral disease clinically similar to dengue and other tropical infectious diseases. The study aims to review the epidemiology of Zika virus infection and to describe the recent epidemics. Zika outbreaks have occurred in South and Central America, Africa, Southeast Asia and the Pacific Islands. Travel-related Zika infections have been reported in Europe and North America. Aedes aegypti mosquito, primary vector of Zika, have become naturalized in several parts of the world. Perinatal and sexual transmission, and potential risk for transfusion-transmission have been demonstrated. Countries should strengthen their laboratory capacity to identify and confirm Zika cases, and establish effective strategies to reduce its transmission through mosquitoes. There is a need for a vaccine and antiviral therapy. The authors did not report assessing the risk of bias.

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