A systematic review of nutritional supplementation in HIV-infected children in resource-limited settings
Periodic vitamin A supplementation is associated with reduced mortality. Macronutrient supplementation is linked to improved anthropometrics. More research is needed to determine how nutritional supplementation benefits this particularly vulnerable population.
Malnutrition can be a major cause of death for children. Malnutrition is often treated with nutritional supplementation (NS), however the effects of NS on HIV-infected children are not well known. This review aimed to assess the effects of macro- and micronutrient supplementation on children <18 years old in low- and middle-income countries. Twenty-three studies were included for review, quality was assessed using Effective Public Health Practice Project guidelines. Results showed vitamin A to have a positive effect on mortality rates. Multiple-micronutrient supplementations did not show improvement for measured health outcomes. Ready-to-use foods were associated with improvement in certain anthropometrics.
Adults, Both sexes, Child health, Children, Conflict, Drought, Endocrine and metabolic conditions, Epidemic/Endemic, Female, Gastrointestinal/Abdominal conditions, Health, HIV and sexually transmitted infections, Infections and infectious diseases (all), Maternal and perinatal health, Neonates/infants, Neoplasms and hematologic conditions, Non-communicable diseases (all), Nutrition, Population displacement, Pregnant/lactating women, Respiratory conditions