Antithrombin III for critically ill patients
Antithrombin III (AT III) cannot be recommended for critically ill patients based on the available evidence.
Critical illness is associated with uncontrolled inflammation and vascular damage which can result in multiple organ failure and death. AT III is an anticoagulant with anti-inflammatory properties but the efficacy and any harmful effects of AT III supplementation in critically ill patients are unknown. This review assesses the benefits and harms of AT III in critically ill patients.
Adults, Both sexes (for groups of both male and female persons), Child health, Children, Conflict, Earthquake, Extreme violence/Accidents, Gastrointestinal/Abdominal conditions, Health, Injuries (all), Maternal and perinatal health, Neonates/infants, Neoplasms and hematologic conditions, Orthopedic injuries, Other injuries, Skin infections