Artemether injection for treating people with severe malaria

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Artemether may not be more effective than quinine at preventing deaths from severe malaria in children. However, in adults artemether is probably more effective than quinine at preventing deaths.

Injection of artesunate is recommended by the World Health Organization (WHO) for treating adults and children that have severe malaria as studies have shown that it results in fewer deaths compared to quinine treatment.

Artemether is an alternative artemisinin‐based medicine but is only available as a pre‐mixed oil‐based solution for intramuscular injection. Artemether is now widely available and is used in many African countries, although it is not specifically recommended by the WHO. The aim of this review was to examine the effects of treating people that have severe malaria with artemether injected intramuscularly compared to treatment with other antimalarial medicines given intramuscularly or intravenously.

The authors examined the available research that evaluated the effects of treating people that have severe malaria with artemether injected intramuscularly compared to treatment with other antimalarial medicines given intramuscularly or intravenously.

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