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Human albumin solution for resuscitation and volume expansion in critically ill patients

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For patients with hypovolaemia, there is no evidence that albumin reduces mortality when compared with cheaper alternatives such as saline. There is no evidence that albumin reduces mortality in critically ill patients with burns and hypoalbuminaemia. The possibility that there may be …

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Topical silver for treating infected wounds

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There is insufficient evidence to recommend the use of silver-containing dressings or topical agents for treatment of infected or contaminated chronic wounds.
Topical silver treatments and silver dressings are increasingly used for the local treatment of contaminated or infected wounds; however, there is …

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Topical silver for preventing wound infection

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There is insufficient evidence to establish whether silver-containing dressings or topical agents promote wound healing or prevent wound infection; some poor quality evidence for silver sulphadiazine suggests the opposite.
Silver-containing treatments are popular and used in wound treatments to combat a broad spectrum …

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Honey as a topical treatment for wounds

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Honey dressings do not increase rates of healing significantly in venous leg ulcers when used as an adjuvant to compression. Honey may delay healing in partial- and full-thickness burns in comparison to early excision and grafting, and in cutaneous Leishmaniasis when used …

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Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention

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There is no evidence for the effectiveness of negative pressure wound therapy (NPWT) on complete healing of wounds expected to heal by primary intention. There are clear cost benefits when non-commercial systems are used to create the negative pressure required for …

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Interventions for preventing injuries in problem drinkers

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Interventions for problem drinking appear to reduce injuries and their antecedents (e.g. falls, motor vehicle crashes, suicide attempts). Because injuries account for much of the morbidity and mortality from problem drinking, larger studies are warranted to evaluate the effect of treating problem …

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Interventions for promoting smoke alarm ownership and function

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This review found that programmes to promote smoke alarms have at most modest beneficial effects on smoke alarm ownership and function, and no demonstrated beneficial effect on fires or fire-related injuries.
Globally, fire-related burns and smoke inhalation accounted for 238,000 deaths in 2000, …

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Topical negative pressure (TNP) for partial thickness burns

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There is no evidence regarding the use of topical negative pressure (TNP) for treating partial thickness burn wounds.
Treatments for burns include a variety of dressings, but newer strategies such as TNP therapy have been developed to try to promote the wound …

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Probiotics for treating persistent diarrhoea in children

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There is limited evidence suggesting probiotics may be effective in treating persistent diarrhoea in children.
Persistent diarrhoea (diarrhoea lasting more than 14 days) accounts for one third of all diarrhoea-related deaths in developing countries in some studies, and probiotics may help treatment. This …

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Probiotics for treating acute infectious diarrhoea

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Used alongside rehydration therapy, probiotics appear to be safe and have clear beneficial effects in shortening the duration and reducing stool frequency in acute infectious diarrhoea. However, more research is needed to guide the use of particular probiotic regimens in specific patient …

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