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Image-guided percutaneous procedure plus metronidazole versus metronidazole alone for uncomplicated amoebic liver abscess

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Therapeutic aspiration in addition to metronidazole to hasten clinical or radiologic resolution of uncomplicated amoebic liver abscesses cannot be supported or refuted by the present evidence.
The most common complication of amoebiasis is the formation of a pus-filled mass inside the liver …

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Antiamoebic drugs for treating amoebic colitis

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Tinidazole is more effective in reducing clinical failure compared with metronidazole and has fewer associated adverse events. Combination drug therapy is more effective in reducing parasitological failure compared with metronidazole alone. However, these results are based on trials with poor methodological …

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Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults

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Xpert® MTB/RIF used as initial diagnostic test for TB detection in patients suspected of having TB, MDR-TR or HIV-associated TB is sensitive and specific. Compared with smear microscopy, Xpert® MTB/RIF substantially increases TB detection among culture-confirmed cases. Xpert® MTB/RIF may also …

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Tidal versus other forms of peritoneal dialysis for acute kidney injury

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There is insufficient evidence to determine whether tidal peritoneal dialysis is superior to any other mode of peritoneal dialysis for the treatment of patients with acute kidney injury.
Acute kidney injury is associated with substantial morbidity and mortality. Recent studies have shown …

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Interventions for protecting renal function in the perioperative period

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There is inconclusive evidence for benefits or increased harm on the use of various interventions (including dopamine and analogues, diuretics, ACE inhibitors, erythropoietin, intravenous fluid and atrial natriuretic peptide) for protecting renal function in the perioperative period for patients undergoing surgery. …

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Emergency interventions for hyperkalaemia

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Nebulised or inhaled salbutamol, or IV insulin-and-glucose are the first-line therapies for the management of emergency hyperkalaemia that are best supported by the evidence. Their combination may be more effective than either alone, and should be considered when hyperkalaemia is severe. …

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Single, double or multiple-injection techniques for axillary brachial plexus block for hand, wrist or forearm surgery in adults

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There is evidence that multiple injection techniques using nerve stimulation for axillary plexus block produce more effective anaesthesia than either double or single injection techniques. There is insufficient evidence for a significant difference in other outcomes, including safety.
Regional anaesthesia comprising axillary …

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Anaesthesia for hip fracture surgery in adults

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There was insufficient evidence available from trials comparing regional versus general anaesthesia for surgical repair of hip fractures in adults to rule out clinically important differences. Regional anaesthesia may reduce acute postoperative confusion but no conclusions can be drawn for mortality or …

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Surgical versus non-surgical treatment for acute anterior shoulder dislocation

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Limited evidence supports primary surgery for young people engaged in highly demanding physical activities who have sustained their first acute traumatic shoulder dislocation. There is no evidence available to determine which treatment is better for other patient groups.
Acute anterior shoulder dislocation …

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Interventions for treating acute elbow dislocations in adults

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Overall, there is a lack of evidence to inform clinical decisions for treating acute simple elbow dislocations in adults. Nonetheless, it should be noted that, while weak and inconclusive, the available evidence from a trial comparing surgery versus conservative treatment did …

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