Coronavirus (COVID-19): Evidence Collection
Created on 16 March 2020. Last updated 3 April 2020.
The COVID-19 (Coronavirus) pandemic is leading to a rapidly expanding and evolving literature. Evidence Aid is preparing summaries of relevant research, which are available below in English with links to translations in other languages. A ‘NEW’ flag will appear on each review as it is added and remain for 48-72 hours.
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NEW Antibiotics for community-acquired pneumonia in children. Added 2 April 2020.
Antibiotics for treating pneumonia outside hospital. Added 28 March 2020.
Antibiotics for treating ventilator-associated pneumonia in adult patients. Added 27 March 2020.
Chinese medicine for the treatment of SARS. Added 31 March 2020.
Corticosteroids for children and adults with pneumonia. Added 27 March 2020.
Extracorporeal membrane oxygenation (ECMO) for patients with acute respiratory failure: Uncertain if it is better or worse than conventional lung support. Added 18 March 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
High levels of PEEP are not better than low levels for reducing mortality in adult ICU patients with acute respiratory distress syndrome (ARDS) or acute lung injury (ALI). Added 18 March 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
Interventions for preventing delirium in adults in an intensive care unit. Added 31 March 2020.
NEW Medical approaches for Middle East respiratory syndrome (MERS). Added 2 April 2020.
Noninvasive mechanical ventilation in high-risk pulmonary infections. Added 26 March 2020.
Oral Ribavirin for treating non-influenza respiratory viral infections. Added 30 March 2020.
Over-the-counter (OTC) medications for acute cough in children and adults: uncertain if they are effective. Added 23 March 2020. [AR] [ES] [FR] [PT]
Over-the-counter (OTC) medications for acute cough in children and adults with pneumonia: uncertain if they are effective. Added 23 March 2020. [AR] [ES] [FR] [PT]
Physical examination tests for detecting difficult airway management in adult patients. Added 24 March 2020.
Prone position during mechanical ventilation in critically ill patients.Added 25 March 2020.
Tap water that is safe to drink is unlikely to be harmful if used to cleanse acute wounds in adults or children. Added 23 March 2020. [AR] [ES] [FR] [PT]
Vitamin D supplementation protects against some acute respiratory tract infections. Added 23 March 2020. [AR] [ES] [FR] [PT]
NEW Community health workers for COVID-19 prevention and control. Added 1 April 2020.
NEW Healthcare workers’ willingness to work during an influenza pandemic. Added 1 April 2020.
NEW Telemonitoring for patients with COPD: effects are uncertain. Added 3 April 2020.
Education interventions to improve healthcare workers’ adherence to Standard Precautions for the control of health care-associated infections. Added 22 March 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
Gloves, gowns and masks for reducing transmission of meticillin-resistant Staphylococcus aureus (MRSA) in the hospital setting: lack of evidence on their specific effects. Added 19 March 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
Infection control strategies for preventing the transmission of meticillin-resistant Staphylococcus aureus (MRSA) in nursing homes for older people: uncertain if they are effective. Added 23 March 2020.
Transportation and transportation hubs and the propagation of respiratory viruses. Added 30 March 2020.
NEW Diagnostics, vaccine and therapeutics for COVID-19 (rapid review). Added 2 April 2020.
Acknowledgements: We should like to acknowledge the help and support of the following in this project –
Advisors: Mike Clarke, Phil Davies, Donna Barbisch, Chris del Mar, Olivia Biermann, Ludovic Reveiz, David Tovey, Judith Glynn, Khamis Elessi, Ruth Hunter, Lelia Duley, Sandy Oliver, Karla Soares-Weiser, Luis Gabriel Cuervo, Elie Akl.
Lead Researchers: Zbys Fedorowicz and Jiewon Lim.
Library services: Obaro Evuarherhe, Margaret Anderson, Hope Lappen, Dorothy Halfhide, Bethany McGowan, Farhad Shokraneh, Jo Wood, Jane Pothecary, Helen Fulbright.
Communications: Sue Wolstenholme, Alexa Phillips, Kristin Carlin.
Summary writers: Rebecca Tafesse Bogale. Helen Nwanosike, Isaiah Rayel, Joseph Mitchell, Raina Klüppelberg,Dimuthu Rathnayake, Yonggang Zhang, Yuxi Li, Huiling Zhang, Lauren Cerruto, Kathleen Dorries, Jim Wood, Carly Sellick, Amanda Borrow, Caroline Freeman, Emma Davies.
Categorising and tagging: Abi Kirubarajan, Shaun Lee.
Website Support: Kat Timberlake.
This project is funded by the H2H Fund, which is supported by UK aid from the UK government.
This project is supported by Queen’s University, Belfast.
Disclaimer: These summaries have been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the coronavirus (COVID-19) but may not have the time, initially, to read the original report in full. The summaries are not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of these summaries think that the evidence that is presented within them is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the coronavirus (COVID-19) on the basis of this summary alone.