Coronavirus (COVID-19): Evidence Collection
Created on 16 March 2020. Last updated 29 May 2020.
The COVID-19 (Coronavirus) pandemic is leading to a rapidly expanding and evolving literature. Evidence Aid is preparing summaries of relevant research, which are available below in English with links to translations in other languages. A ‘NEW’ flag will appear on each review as it is added and remain for 48-72 hours.
This collection includes summaries of systematic reviews that might be relevant to the direct impact of COVID-19 (including reviews of emerging research, as well as existing reviews of relevant interventions) on health and other outcomes, the impact of the COVID-19 response on other conditions, and issues to consider for the recovery period after COVID-19.
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Assertive community treatment for adults with severe mental illness. Added 13 May 2020.
Asthma patients who are stable have a higher risk of an exacerbation if they stop their low-dose inhaled corticosteroids rather than continuing. Added 7 April 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
Atypical antibiotics alone seem no better for mortality and clinical efficacy than typical antibiotics alone in patients with community acquired pneumonia. Added 19 March 2020. [AR] [ES] [FR] [IT] [PT] [ZH-simp] [ZH-trad]
Clinical features for diagnosing pneumonia among adults in primary care. Added 6 May 2020.
Clinical features of COVID-19 (search done: 10 March 2020). Added 22 May 2020.
Convalescent plasma or hyperimmune immunoglobulin for people with COVID‐19: effects are uncertain (search done 23 April 2020). Added 15 May 2020.
CRB-65 rule for predicting the severity of pneumonia. Added 7 May 2020.
NEW Crisis-planning interventions for people with psychotic illness or bipolar disorder. Added 28 May 2020.
CT imaging features of 4121 patients with COVID-19 (search done: 16 March 2020). Added 21 May 2020.
Extracorporeal membrane oxygenation (ECMO) for patients with acute respiratory failure: Uncertain if it is better or worse than conventional lung support. Added 18 March 2020. [AR] [ES] [FR] [IT] [PT] [ZH-simp] [ZH-trad]
High levels of PEEP are not better than low levels for reducing mortality in adult ICU patients with acute respiratory distress syndrome (ARDS) or acute lung injury (ALI). Added 18 March 2020. [AR] [ES] [FR] [IT] [PT] [ZH-simp] [ZH-trad]
Mechanical ventilation with a lower tidal volume reduces 28-day mortality in adults with acute respiratory distress syndrome or acute lung injury. Added 19 March 2020. [AR] [ES] [FR] [IT] [PT] [ZH-simp] [ZH-trad]
Oxygen supplementation at higher levels for critically ill patients: Uncertain effects but may increase mortality and adverse effects. Added 16 March 2020. [AR] [ES] [FR] [IT] [PT] [ZH-simp] [ZH-trad]
Oxygen therapy for critical care of adults with pneumonia. Added 10 May 2020.
Pressure-controlled versus volume-controlled ventilation for acute respiratory failure: uncertain if there is an important difference in outcomes. Added 20 March 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
Signs and symptoms of community-acquired pneumonia. Added 20 May 2020.
Clinical characteristics and diagnostic challenges of pediatric COVID-19 (search done: 15 March 2020). Added 15 May 2020.
Scoping review of COVID-19 research (search done: 24 February 2020). Added 21 May 2020.
Advanced practice nurses can provide safe and effective primary care. Added 9 May 2020.
Appointment-based medication synchronization. Added 12 May 2020.
Clinical guidelines in the community pharmacy setting. Added 4 May 2020.
Co-locating specialty and primary care. Added 7 May 2020.
Community monitoring interventions to curb corruption and increase access and quality of service delivery in low‐and middle‐income countries. Added 28 April 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
Community pharmacist services for non‐hospitalised patients. Added 13 May 2020.
Community pharmacy interventions for health promotion improve some health-related behaviours and the quality of life of users of community pharmacies. Added 4 April 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
Computerized clinical decision support systems for primary preventive care. Added 5 May 2020.
Copayment for health care services. Added 9 May 2020.
Decreasing the rate of avoidable readmissions to acute care hospitals. Added 19 May 2020.
Differential user fees for primary and secondary care: effects are uncertain. Added 10 May 2020.
Effectiveness of senior doctor triage in enhancing emergency room performance. Added 20 May 2020.
Electronic prescribing in the ambulatory care setting. Added 7 May 2020.
Financial incentives for prescribers: effects are uncertain. Added 8 May 2020.
General practice provider collaborations in England. Added 4 May 2020.
Health-related lifestyle advice delivered by peer or lay advisors. Added 19 May 2020.
Integrated care with indigenous populations in North America. Added 12 May 2020.
Integrating primary health services in low‐ and middle‐income countries. Added 15 May 2020.
International variation in length of primary care consultations. Added 6 May 2020.
Interventions to reduce wait times for primary care appointments. Added 8 May 2020.
mHealth projects in Africa improved some aspects of health care. Added 9 May 2020.
Nurse-initiated medications in the emergency department. Added 13 May 2020.
Nurse-led services are safe and effective in the ambulatory care setting. Added 10 May 2020.
Payment mechanisms for family physicians. Added 19 May 2020.
Pharmacist-led medication reconciliation after hospital discharge. Added 5 May 2020.
Pharmacist‐provided non‐dispensing services in low‐ and middle‐income countries. Added 10 May 2020.
Pharmacist services provided in general practice clinics. Added 19 May 2020.
Physician assistants can be effective in primary care. Added 12 May 2020.
Quality and outcomes framework for primary care in the United Kingdom. Added 11 May 2020.
Rural outreach programs for medical students. Added 13 May 2020.
Structuring of electronic health records. Added 5 May 2020.
Surgical procedures done by general practitioners with specialty interests. Added 5 May 2020.
Telemedicine applications in emergency rooms. Added 4 May 2020.
Telemedicine in Japan: economic evaluations. Added 15 May 2020.
Training and government regulation of private for-profit healthcare providers in low- and middle-income countries may improve quality of care. Added 29 April 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
Use of medical scribes in health care settings. Added 15 May 2020.
NEW Aerosol generating procedures and transmission of respiratory infections to healthcare workers. Added 29 May 2020.
NEW Computer device contamination in healthcare settings. Added 27 May 2020.
Education interventions to improve healthcare workers’ adherence to Standard Precautions for the control of health care-associated infections. Added 22 March 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
Gloves, gowns and masks for reducing transmission of meticillin-resistant Staphylococcus aureus (MRSA) in the hospital setting: lack of evidence on their specific effects. Added 19 March 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
NEW Gloves’ use by healthcare workers to prevent cross transmission. Added 29 May 2020.
Hand-hygiene interventions reduce illness due to acute respiratory infections in childcare, school and domestic settings in low- and middle-income countries. Added 6 April 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
Healthcare workers’ adherence with infection prevention and control (IPC) guidelines for respiratory infectious diseases: barriers and facilitators. Added 21 April 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
Infection control strategies for preventing the transmission of meticillin-resistant Staphylococcus aureus (MRSA) in nursing homes for older people: uncertain if they are effective. Added 23 March 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
NEW Infection prevention and control in oral healthcare facilities. Added 29 May 2020.
Screening travelers for infectious diseases. Added 3 May 2020.
Advocacy interventions to reduce or eliminate violence and promote the physical and psychosocial well‐being of women who experience intimate partner abuse. Added 18 April 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
Handwashing promotion targeted at children, on diarrhea, soil-transmitted helminth infections and behavior change, in low- and middle-income countries: effects are uncertain. Added 15 April 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
School closures to reduce the transmission of influenza. Added 8 May 2020.
Visiting urban green space exposure has been shown to boost the immune system and mental health, and reduce the risks of cardiovascular and respiratory diseases. Added 26 March 2020. [AR] [ES] [FR] [PT] [ZH-simp] [ZH-trad]
NEW Distance travelled by respiratory droplets (search done before 31 March 2020). Added 27 May 2020.
Acknowledgements: We should like to acknowledge the help and support of the following in this project –
Advisors: Elie Akl, Ashley Agus, Donna Barbisch, Olivia Biermann, Malcolm Brewster, Pamela Catalán Rubio, Mike Clarke, Luis Gabriel Cuervo, Phil Davies, Chris del Mar, Jaime Del Rio, Lelia Duley, Khamis Elessi, Saniya Fakhar, Ronald Flumignan, Judith Glynn, Ruth Hunter, Kim Kilov, Rhona Mijumbi-Deve, Ronald Munatsi, Ngoy Nsenga, Patrick Okwen, Sandy Oliver, Cheow Peng Ooi, Indu Rai, Ludovic Reveiz, Karla Soares-Weiser, Narasimman Swaminathan, David Tovey.
Lead Researchers: Ahmad Firas Khalid (from 30 April), Zbys Fedorowicz (to 30 April), Jiewon Lim and Christine McKee (from 20 April).
Library services/searching: Jo Wood (lead), Nicole Askin, Anna Brown, Obaro Evuarherhe, Helen Fulbright, Dorothy Halfhide, Golo Henning, Bethany McGowan, Jane Pothecary, James Robinson, Farhad Shokraneh, Ruth Suhami, Adam Tocock, John Trevor-Allen, Nishant Tripathi, Alison Turner, Naeem Yar,
Screening: Margaret Anderson (lead), Ciara Keenan, Felix Lambert, Alison Mace, Joanna Przezdziecka-Dolyk, Sravya Pudota, Sinjini Sarkar, TA Ojo Taiwo, Abhijna Vithal Yergolkar.
Communications and translations (for social media): Kristin Carlin, Wong Chun Hoong, Yiyi Jiang, Bushrah Kalakh, Catherine Keys, Epaminondas La Bella, Zhenhui Le, Xiang-Guo Lei, Brian Li, Haishan Li, Man Li, Xiang Li, Victoria Olvera, Sarah Peureux, Alexa Phillips, Rodrigo Torres Castro, Sue Wolstenholme,
Summary writers and support: Hebatullah Abdulazeem, Charles Badu-Boateng, Rachel Beanland, Sirisha Bellamkonda, Alessio Bellato, Amanda Borrow, Lauren Cerruto, Loren De Freitas, Lisa Deiminger, Noah Dixon, Kathleen Dorries, Alastair Dunbar, Caroline Freeman, Rachael Frost, Rocio Fuentes Aspe, Joly Ghanawi, Maddalena Giacomozzi, Saurabh Gupta, Catherine Haynes, Russell He, Catherine Henderson, Rosemary James, Anish Jammu, Chris Jenkins, Sushant Kaushal, Michelle King-Okoye, Sadie Lawes-Wickwar, Simone Lepage, Brian Li, Yuxi Li, Ghazal Mazloumi, Joseph Mitchell, Linda Murray, Helen Nwanosike, Evani Patel, Amanda Perry, Leah Phillips, Vivek Podder, Dimuthu Rathnayake, Jennifer Raven, Isaiah Rayel, Samreen Rizwan, Stephanie Sampson, David Schramm, Hema Sivasubramanian, Sini Skarp, Liz Stovold, Lenny Vasanthan, Vivian Welch, Magdalen Wind-Mozley, Jim Wood, Ruth Yan, Huiling Zhang, Yonggang Zhang,
Categorising and tagging: Liina Haldna, Shona Kirtley, Abi Kirubarajan, Shaun Lee.
Website Support: Jaimu Aderonmu, Ayodele Ayobami, Justyna Chylewska, Antonio Aurelio De Paiva Fagundes, Gabriel Kwok, Kat Timberlake, Nikolett Warner.
This project is funded by the H2H Fund, which is supported by UK aid from the UK government.
This project is supported by Queen’s University, Belfast.
Disclaimer: These summaries have been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the coronavirus (COVID-19) but may not have the time, initially, to read the original report in full. The summaries are not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of these summaries think that the evidence that is presented within them is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the coronavirus (COVID-19) on the basis of this summary alone.