High-flow nasal cannulae for respiratory support in adult intensive care patients: insufficient evidence to determine its effects

Citation: Corley A, Rickard CM, Aitken LM, et al. High-flow nasal cannulae for respiratory support in adult intensive care patients. Cochrane Database of Systematic Reviews 2017; (5): CD010172.
DOI: 10.1002/14651858.CD010172.pub2

What is this? Viral infections such as COVID-19 can progress to acute respiratory failure, with patients needing help with their breathing in an intensive care unit (ICU). This might include the use of high-flow nasal cannulae (HFNC), which supply high flows of blended humidified air and oxygen.

In this Cochrane systematic review, the authors searched for randomized and quasi-randomized trials of the effects of high-flow nasal cannulae use in adult ICU patients compared to other non-invasive forms of respiratory support. Their main searches in March 2016 identified 11 studies (1972 participants) for inclusion in the review. They found 4 more studies in a December 2016 search, which will be considered in an update to the review.

What works: Nothing noted.

What doesn’t work: Nothing noted.

What’s uncertain: There is insufficient evidence to determine the effects of high-flow nasal cannulae compared with other forms of respiratory support for adult ICU patients.

 

Disclaimer: This summary has been written by staff and volunteers of Evidence Aid in order to make the content of the original document accessible to decision makers who are searching for the available evidence on the coronavirus (COVID-19) but may not have the time, initially, to read the original report in full. This summary is not intended as a substitute for the medical advice of physicians, other health workers, professional associations, guideline developers, or national governments and international agencies. If readers of this summary think that the evidence that is presented within it is relevant to their decision-making they should refer to the content and details of the original article, and the advice and guidelines offered by other sources of expertise, before making decisions. Evidence Aid cannot be held responsible for any decisions made about the coronavirus (COVID-19) on the basis of this summary alone.

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