Neuropsychological long-term sequelae of Ebola virus disease survivors

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Survivors of the Ebola virus disease (EVD) commonly suffered from depression, insomnia, fatigue, anxiety, and post-traumatic stress. Data from high quality studies is scarce, which prevents drawing conclusions about the impact and magnitude of these conditions.

This systematic review aimed to assess the neuro- and socio-psychological long-term conditions experiences by Ebola virus diseases survivors. A total of 10 papers were included. Evidence was found for the experience of depression, insomnia, fatigue, anxiety, and post-traumatic stress. However, many methodological issues prevent clear conclusions, such as lack of control groups. Of note is that depression was in none of the studies formally diagnosed by a psychiatrist. A prospective, controlled cohort study protocol in preparation for potential future outbreaks is advised.

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