Protein hydrolysate versus standard formula for preterm infants

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The currently available evidence suggested that feeding preterm infants with hydrolysed formula (rather than standard formula) during their initial hospital admission has no important benefits or harms. his finding is not yet conclusive.

When human milk is not available for feeding preterm infants, protein hydrolysate formulas are often preferred to standard cow’s milk formulas (with intact proteins) as they are perceived as being tolerated better. This review aims to assess the effect of feeding preterm infants with hydrolysed formula (versus standard cow’s milk formulas) on the risk of feed intolerance, necrotising enterocolitis, and other morbidity and mortality in preterm infants.

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