» Adolescents

Drugs for treating Schistosomiasis mansoni infection

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The available evidence supports single dose praziquantel at 40 mg/kg as standard treatment for S. mansoni infection as recommended by the WHO. Oxamniquine, a largely discarded alternative, appears efficacious and production and distribution should continue to ease selective pressure on praziquantel. …

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Antimicrobials for treating symptomatic non-typhoidal Salmonella infection

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There appears to be no evidence of a clinical benefit of antibiotic therapy in otherwise healthy children and adults with non-severe salmonella diarrhoea. Antibiotics appear to increase adverse effects and they also tend to prolong salmonella detection in stools.
Non-typhoidal salmonellosis appears …

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Immunoglobulins for preventing hepatitis A

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Immunoglobulins seem effective for preventing hepatitis A in both children and adults. However, the evidence, on which the conclusion is based, is not strong as the included trials appear to have risk of bias and their number is insufficient.
Hepatitis A is …

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Surgical versus non-surgical treatment for acute anterior shoulder dislocation

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Limited evidence supports primary surgery for young people engaged in highly demanding physical activities who have sustained their first acute traumatic shoulder dislocation. There is no evidence available to determine which treatment is better for other patient groups.
Acute anterior shoulder dislocation …

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Surgical versus conservative interventions for displaced intra-articular calcaneal fractures

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There is insufficient high quality evidence to establish whether surgical or conservative treatment is better for adults with displaced intra-articular calcaneal (heel bone) fracture.
Fractures of the calcaneus (heel bone) comprise up to 2% of all fractures, and are mostly caused by a …

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Combined pharmacotherapy and psychological therapies for post traumatic stress disorder (PTSD)

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There is not enough evidence available to support or refute the effectiveness of combined psychological therapy and pharmacotherapy compared to either of these interventions alone.
Symptoms of PTSD include re-experiencing the event, avoidance and arousal, as well as distress and impairment resulting from …

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