» Both sexes (for groups of both male and female persons)

Interventions for preventing the spread of infestation in close contacts of people with scabies

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There is no evidence to support the effectiveness of providing prophylactic treatments for close contacts of people with scabies for the prevention of re-infestation or spread of infestation in contacts.
Scabies is a parasitic infection that spreads from person to person through …

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Interventions for treating femoral shaft fractures in children and adolescents

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There is insufficient evidence on the benefits and harms from the independent comparisons of surgical and non-surgical interventions for treating femoral shaft fractures. Furthermore, there is insufficient evidence on whether long term function as an outcome differs between the surgical and conservative …

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Kangaroo mother care to reduce morbidity and mortality in low birth weight infants

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There is evidence to support the use of Kangaroo Mother Care (KMC) as an alternative to neonatal care in low-birth weight infants particularly, in resource limited settings in the reduction of mortality and morbidity rates. However, more evidence to assess efficacy …

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Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years of age

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There is some evidence to support the effectiveness of preventative zinc supplementation particularly, where the risk of zinc deficiency is high. However, more evidence on optimal intervention characteristics such as supplement dose is needed.
Zinc deficiency is responsible for significant morbidity and mortality …

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Antibiotics for preventing suppurative complications from undifferentiated acute respiratory infections in children under five years of age

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There is insufficient evidence from clinical trials on the effectiveness (efficacy and safety) of antibiotics in reducing the risk of otitis or pneumonia in children aged between two and 59 months with undifferentiated acute respiratory infections (ARIs).
ARIs are a group of …

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Interventions to Reduce Distress in Adult Victims of Sexual Violence and Rape: A Systematic Review

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There is moderate evidence that cognitive and behavioural interventions, in particular Cognitive Processing Therapy, Prolonged Exposure therapy, Stress Inoculation Therapy, and Eye Movement Desensitization and Reprocessing can be associated with decreased symptoms of Post-Traumatic Stress Disorder, anxiety and depression in victims …

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Ebola virus disease: Key questions and answers concerning water, sanitation and hygiene

Ebola Virus Disease (EVD): Key Questions and Answers Concerning Water, Sanitation and Hygiene (WHO 2014): Controlling the hazards from the presence of the Ebola virus in body fluids lies in the separation and containment of all body fluids (including feces and urine). Feces from suspected …

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Nerve blocks for initial pain management of femoral fractures in children

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Low quality evidence from one small trial suggests that fascia iliaca compartment block (FICB) provides better and longer lasting pain relief with fewer adverse events than intravenous opioids for femur fractures in children. Well conducted and reported randomised trials that compare nerve …

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Chlorpromazine versus placebo for schizophrenia

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55 studies of predominantly low quality suggest that chlorpromazine reduces relapse and improves mental health, symptoms and functioning in patients with schizophrenia. However, there are side effects of chlorpromazine associated with its use and its use should be judicious.
The main treatment …

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Beta lactam antibiotic monotherapy versus beta lactam-aminoglycoside antibiotic combination therapy for sepsis

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The addition of an aminoglycoside to a beta lactam does not improve the clinical efficacy achieved with the beta lactam alone. However, the combination therapy of an aminoglycoside and a beta lactam was associated with an increased risk of renal damage …

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