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High-carbohydrate, high-protein, low-fat versus low-carbohydrate, high-protein, high-fat enteral feeds for burns

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The available evidence suggests that use of high-carbohydrate, high-protein, low-fat enteral feeds in patients with at least 10% total body surface area burns might reduce the incidence of pneumonia compared with use of a low-carbohydrate, high-protein, high-fat diet. The available evidence is …

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Selenium supplementation for critically ill adults

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There is limited evidence to recommend supplementation of critically ill patients with selenium or ebselen.
Selenium is a trace mineral essential to health and has an important role in immunity, defence against tissue damage and thyroid function. Improving selenium status could help …

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Nutritional support for critically ill children

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The one trial included in this review was of low methodological quality and found no statistically significant difference for mortality, sepsis, ventilator days, length of stay, unexpected adverse events, resting energy expenditure, nitrogen balance, or albumin levels.
Nutritional support in the critically …

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Early versus delayed enteral nutrition support for burn injuries

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This systematic review has not found sufficient evidence to support or refute the effectiveness of early versus late enteral nutrition support in adults with burn injury. The trials showed some promising results that would suggest early enteral nutrition support may blunt the …

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Intravenous lidocaine for the treatment of background or procedural burn pain

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As current clinical evidence is based on only one single randomised controlled trial as well as case series and reports, intravenous lidocaine must be considered a pharmacological agent under investigation in burns care, the effectiveness of which is yet to be determined …

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Hyperbaric oxygen therapy for thermal burns

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There is insufficient evidence to support or refute the effectiveness of hyperbaric oxygen therapy (HBOT) for the management of thermal burns.
HBOT consists of intermittently administering 100% oxygen at pressures greater than 1 atmosphere in a pressure vessel. This technology has been used …

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Aerosolized prostacyclin for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS)

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There is no current evidence to support or refute the routine use of aerosolized prostacyclin for patients with acute lung injury (ALI) and acute respiratory distress (ARDS).
ALI and ARDS are critical conditions that are associated with high mortality and morbidity. Aerosolised prostacyclin …

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Human albumin solution for resuscitation and volume expansion in critically ill patients

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For patients with hypovolaemia, there is no evidence that albumin reduces mortality when compared with cheaper alternatives such as saline. There is no evidence that albumin reduces mortality in critically ill patients with burns and hypoalbuminaemia. The possibility that there may be …

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Topical silver for preventing wound infection

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There is insufficient evidence to establish whether silver-containing dressings or topical agents promote wound healing or prevent wound infection; some poor quality evidence for silver sulphadiazine suggests the opposite.
Silver-containing treatments are popular and used in wound treatments to combat a broad spectrum …

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Honey as a topical treatment for wounds

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Honey dressings do not increase rates of healing significantly in venous leg ulcers when used as an adjuvant to compression. Honey may delay healing in partial- and full-thickness burns in comparison to early excision and grafting, and in cutaneous Leishmaniasis when used …

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