» Child health

Surgical versus non-surgical treatment for acute anterior shoulder dislocation

Read the full review here
Limited evidence supports primary surgery for young people engaged in highly demanding physical activities who have sustained their first acute traumatic shoulder dislocation. There is no evidence available to determine which treatment is better for other patient groups.
Acute anterior shoulder dislocation …

Full Story »

Psychological treatment for anxiety in people with traumatic brain injury

Read the full review here
There is some evidence for the effectiveness of cognitive behavioural therapy (CBT) for treating acute stress disorder following mild traumatic brain injury (TBI) and of CBT combined with neurorehabilitation for targeting general anxiety symptomatology in people with mild-to-moderate TBI.
Psychological treatments are …

Full Story »

Corticosteroids for acute traumatic brain injury

Read the full review here
The increase in mortality with steroids in one trial suggest that steroids should no longer be routinely used in people with traumatic head injury (TBI).
TBI is a leading cause of death and disability. Corticosteroids have been widely used in treating people …

Full Story »

Hypothermia for traumatic head injury

Read the full review here
There is no evidence that hypothermia is beneficial in the treatment of head injury. Hypothermia should not be used except in the context of a high-quality randomised controlled trial with good allocation concealment.
Hypothermia has been used in the treatment of head …

Full Story »

Steroids for acute spinal cord injury

Read the full review here
Methylprednisolone has been shown to enhance sustained neurologic recovery in a phase III randomised trial; findings replicated in a second trial. Therapy must be started within 8 hours of injury using an initial bolus of 30 mg/kg by IV for 15 …

Full Story »

Antifibrinolytic drugs for acute traumatic injury

Read the full review here
Tranexamic acid safely reduces mortality in bleeding trauma patients without increasing the risk of adverse events.  Tranexamic acid should be given as early as possible and within three hours of injury, as treatment later than this is unlikely to be effective.
Uncontrolled …

Full Story »

Colloids versus crystalloids for fluid resuscitation in critically ill patients

Read the full review here
There is no evidence that resuscitation with colloids reduces the risk of death, compared to resuscitation with crystalloids, in patients with trauma, burns or following surgery. Furthermore, the use of hydroxyethyl starch might increase mortality. As colloids are not associated with …

Full Story »

Surgical versus conservative interventions for displaced intra-articular calcaneal fractures

Read the full article
There is insufficient high quality evidence to establish whether surgical or conservative treatment is better for adults with displaced intra-articular calcaneal (heel bone) fracture.
Fractures of the calcaneus (heel bone) comprise up to 2% of all fractures, and are mostly caused by a …

Full Story »

Aloe vera for treating acute and chronic wounds

Read the full review here
There is currently an absence of high-quality clinical trial evidence to support the use of Aloe vera topical agents or Aloe vera dressings as treatments for acute and chronic wounds.
Aloe vera is a cactus-like perennial succulent belonging to the Liliaceae family, …

Full Story »

Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention

Read the full article here
Evidence for the effectiveness of negative pressure wound therapy (NPWT) for complete healing of acute wounds remains unclear, as does the effect of NPWT on time to complete healing. Rates of graft loss may lower when NPWT is used, but hospital-based …

Full Story »