» Health

Pin site care for preventing infections associated with external bone fixators and pins

Read the full review here
There is insufficient evidence to be able to identify a strategy of pin site care that minimises infection rates.
Metal pins are used to apply skeletal traction or external fixation devices in the management of orthopaedic fractures. These percutaneous pins protrude through …

Full Story »

Epidemiology of Zika virus, 1947–2007

Read the full review here
The evidence supports the belief that Zika virus circulated in Africa and Asia for decades, and was only recently introduced to the Americas.
Since 1947, Zika virus has been identified sporadically in humans in Africa and Asia, however, clinically consequential Zika virus …

Full Story »

Arboviral and other illnesses in travellers returning from Brazil, June 2013 to May 2016: implications for the 2016 Olympic and Paralympic Games

Read the full review here
During the 2013–15 Brazilian winter months (August and September) there were no cases of Zika virus infection or chikungunya and 3 cases of dengue fever documented in travellers. During October-July 2013 -15 there were 14 cases of Zika, 15 of chikungunya …

Full Story »

Transmission of Zika virus through breast milk and other breastfeeding-related bodily-fluids: a systematic review

Read the full review here
There was insufficient evidence to determine whether Zika virus could be transmitted via breastfeeding.
ZIKV transmission occurs primarily via the bite of mosquitoes, however perinatal, transfusion, and sexual transmission have also been reported. With the recent increases of ZIKV cases in Central …

Full Story »

Accuracy of ultrasound scanning relative to reference tests for prenatal diagnosis of microcephaly in the context of Zika virus infection: a systematic review of diagnostic test accuracy

Read the full Review
Evidence suggests that prenatal ultrasound appears more accurate in detecting the absence of microcephaly than its presence.
In 2015, a 20-fold increase in neonatal microcephaly was observed in association with Zika virus infection in pregnant women in Latin America. There is no …

Full Story »

Zika virus infection in pregnancy: a systematic review of disease course and complications

Read the full review here
Evidence shows that maternal Zika virus infection tended to have more adverse effects on the fetus and the infant than on the mother.
A 20-fold increase in the incidence of microcephaly relative to previous years was reported with the onset of …

Full Story »

State of knowledge on Zika virus for an adequate laboratory response

Read the full review here
The evidence provides essential Zika virus knowledge to the world laboratory community and identifies knowledge gaps.
The current epidemic of Zika virus has resulted in a large increase in diagnostic requests in the Americas and elsewhere when travelers return from affected areas. …

Full Story »

Is Dengue vector control deficient in effectiveness or evidence?: Systematic review and meta-analysis

Read the full review here
There is currently scarce reliable evidence on the effectiveness of any Dengue vector control strategy.
Dengue is the most widespread mosquito-borne arboviral disease and vector control methods are the main approach to prevent it. This study reviewed the evidence for effectiveness …

Full Story »

Congenital cerebral malformations and dysfunction in foetuses and newborns following the 2013 to 2014 Zika Virus epidemic in French Polynesia

Read the full review here
There was insufficient evidence to associate cerebral malformations or dysfunction without microcephaly to Zika virus infection.
 An unusual increase in annual congenital cerebral malformations, brainstem dysfunction and severe microcephaly among foetuses and new-borns was observed after the 2013 – 2014 Zika …

Full Story »

The value of educational messages embedded in a community-based approach to combat Dengue Fever: A systematic review and meta regression analysis

Read the full review here
Evidence suggests that the effect of educational messages embedded within community-based approached was most effecting about 18 to 24 months after it was delivered but then subsequently declined.
Prevention of Dengue relies on mosquito control. The mosquito, Aedes aegypyti (which also causes …

Full Story »