» Malaria and protozoal infections

Polymer-based oral rehydration solution for treating acute watery diarrhoea

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Polymer-based ORS shows some advantages compared to ORS ≥ 310 [the original ORS was based on glucose and had an osmolarity of ≥ 310 mOsm/L] for treating all-cause diarrhoea, and in diarrhoea caused by cholera. Comparisons favoured the polymer-based ORS over …

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Image-guided percutaneous procedure plus metronidazole versus metronidazole alone for uncomplicated amoebic liver abscess

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Therapeutic aspiration in addition to metronidazole to hasten clinical or radiologic resolution of uncomplicated amoebic liver abscesses cannot be supported or refuted by the present evidence.
The most common complication of amoebiasis is the formation of a pus-filled mass inside the liver …

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Antiamoebic drugs for treating amoebic colitis

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Tinidazole is more effective in reducing clinical failure compared with metronidazole and has fewer associated adverse events. Combination drug therapy is more effective in reducing parasitological failure compared with metronidazole alone. However, these results are based on trials with poor methodological …

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Hand washing promotion for preventing diarrhoea

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Interventions to promote handwashing, such as targeted education and provision of free soap, improve hand hygiene and reduce diarrhoeal episodes in children and adults living in low- and middle-income countries by about one third. This significant reduction is comparable to the …

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Interventions to improve disposal of human excreta for preventing diarrhoea

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This review provides some evidence that interventions to improve excreta disposal are effective in preventing diarrhoeal disease.
Over a third of the world’s population lacks access to improved facilities for the disposal of human excreta, such as a basic pit latrine, a toilet …

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Interventions to improve water quality for preventing diarrhoea

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Interventions to improve water quality are generally effective in preventing diarrhoea, and interventions to improve water quality at the household level are more effective than those at the source.
Diarrhoeal diseases are a leading cause of mortality and morbidity, especially among young children …

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