» Neonates/infants

Antibiotics versus placebo for acute bacterial conjunctivitis

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Acute bacterial conjunctivitis is frequently a self-limiting condition, but the use of antibiotics is associated with modestly improved rates of clinical and microbiological remission compared to placebo.
Acute bacterial conjunctivitis is an infective condition in which the eyes become red and inflamed. …

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Antimicrobials for treating symptomatic non-typhoidal Salmonella infection

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There appears to be no evidence of a clinical benefit of antibiotic therapy in otherwise healthy children and adults with non-severe salmonella diarrhoea. Antibiotics appear to increase adverse effects and they also tend to prolong salmonella detection in stools.
Non-typhoidal salmonellosis appears …

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Oral rehydration salt solution for treating cholera: ≤ 270 mOsm/L solutions vs ≥ 310 mOsm/L solutions

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In people with cholera, ORS ≤ 270 is associated with biochemical hyponatraemia when compared with ORS ≥ 310 [90 mmol/L of sodium, 20 mmol/L of potassium, 80 mmol/L of chloride, 10 mmol/L of citrate, and 111 mmol/L of glucose, with a …

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Polymer-based oral rehydration solution for treating acute watery diarrhoea

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Polymer-based ORS shows some advantages compared to ORS ≥ 310 [the original ORS was based on glucose and had an osmolarity of ≥ 310 mOsm/L] for treating all-cause diarrhoea, and in diarrhoea caused by cholera. Comparisons favoured the polymer-based ORS over …

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Interventions to improve water quality for preventing diarrhoea

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Interventions to improve water quality are generally effective in preventing diarrhoea, and interventions to improve water quality at the household level are more effective than those at the source.
Diarrhoeal diseases are a leading cause of mortality and morbidity, especially among young children …

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