» Viral fevers/VHF

Ebola virus disease: Key questions and answers concerning water, sanitation and hygiene

Ebola Virus Disease (EVD): Key Questions and Answers Concerning Water, Sanitation and Hygiene (WHO 2014): Controlling the hazards from the presence of the Ebola virus in body fluids lies in the separation and containment of all body fluids (including feces and urine). Feces from suspected …

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Routine vitamin A supplementation for the prevention of blindness due to measles infection in children

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No evidence was found to investigate whether vitamin A can prevent blindness in children infected with measles.
Annually 500,000 children become blind worldwide, 75% of them living in low-income countries. Measles infection in children has been associated with vitamin A deficiency and …

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Combined and alternating paracetamol and ibuprofen therapy for febrile children

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There is some evidence to support the use of alternating and combination therapy compared with monotherapy alone at reducing temperatures in children with a fever. However, on the outcome of child discomfort, the evidence still remains unsatisfactory. Furthermore, there is insufficient evidence …

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Physical interventions to interrupt or reduce the spread of respiratory viruses

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There is some evidence to suggest that some low cost and simple interventions such as hand washing would be useful in helping to reduce the transmission of epidemic respiratory viruses. Implementing transmission barriers, isolation and hygienic measures are effective at containing respiratory virus …

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Zinc supplementation as an adjunct to antibiotics in the treatment of pneumonia in children 2 to 59 months of age

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There is insufficient evidence from randomised controlled trials (RCTs) to support the use of zinc as an adjunct to antibiotics in the treatment of pneumonia in children aged between 2 and 59 months.
Acute respiratory infections particularly pneumonia, are responsible for high mortality in …

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Corticosteroids for pneumonia

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There is still insufficient evidence on efficacy and safety of corticosteroids in patients with pneumonia. The current available evidence suggests that corticosteroids in patients with pneumonia are usually helpful in accelerating the time to symptom resolution.
The use of corticosteroids is associated with …

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Antibiotics for community acquired pneumonia in children

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The evidence from RCTs on the effectiveness of various antibiotics for community-acquired pneumonia (CAP) in children varies. For the treatment of patients with CAP in ambulatory setting, amoxycillin can be used as an alternative to co-trimoxazole. The limited data available on other antibiotics …

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Antibiotics for community-acquired pneumonia in adult outpatients

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There is insufficient evidence from randomised controlled trials (RCTs) on the efficacy of various antibiotic treatments in patients who are older than 12 years of age with a diagnosis of  community acquired pneumonia (CAP).
CAP is associated with very high mortality and …

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Lay health workers in primary and community health care for maternal and child health and the management of infectious diseases

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Lay health workers may provide benefits in promoting immunisation uptake and breastfeeding, improving tuberculosis cure rates, and child health when compared to usual care. There is insufficient evidence to draw any conclusions for other health issues.
Lay health workers (LHWs) are widely used …

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Vaccines for preventing Japanese encephalitis

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It is not possible to compare the effectiveness of currently used vaccines in preventing clinical disease as only one of three vaccines has been directly investigated for effectiveness in an RCT.
Japanese encephalitis is a viral disease of the central nervous system …

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